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Thus, carriers of a highly functional CYP2C19*2 variant require higher doses of VPA to achieve target therapeutic plasma concentrations (450 μg/mL), indicating that the CYP2C19 isoenzyme is also involved in the metabolic pathway of VPA
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doi: 10.3390/nu15235005 16 WangTWangJHuXHuangXJChenGX
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