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A poor intestine absorption caused by infection, inflammation or a pathology in the intestine morphology may cause an adverse Ca 2+ balance[4], which under chronic conditions leads to a deleterious bone mineralization
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Further, the presence of astrocytic cytoplasmic inclusions, protein aggregates like alpha-synuclein (SNCA), Aβ, and Tau in neurons, can also contribute to neuropathology (Li and Haney, 2020) and appears to be one of the critical features in many neurodegenerative diseases
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