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[] One phase III trial over the previous decade examined PSA rates, PSADT, and 8-hydroxy-2-deoxyguanosine (8-OHdG) in PCa tissue

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Moreover, the use of a synthetic derivative of salinomycin (AM5) in breast CSCs induced iron depletion both in vitro and in vivo, mechanistically via the degradation of ferritin within lysosomes, leading to increased ROS production and subsequent selective breast CSCs death via ferroptosis [101]