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Neuroimmune, metabolic and oxidative stress pathways in major depressive disorder | Nature Reviews Neurology
Research has shown that high concentrations of CORT increase intracellular ROS and FOXO3a nuclear accumulation by inhibiting these signaling pathways based on the observed decreased phosphorylation of p38, ERK, PI3K, and AKT
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doi: 10.1002/cyto.a.20901 39 MallickN.MohnF
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