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LIST OF ABBREVIATIONS ABTS 2,2′-azino-bis (3-ethylbenzthiazoline-6-sulphonic acid) AGEs Advanced glycation end-products BSA Bovine serum albumin DCFH-DA 2′,7′-dichlorofluorescein diacetate DMEM Dulbecco’s Modified Eagle Medium DPPH 2,2-diphenyl-1-picrylhydrazyl FBS Fetal bovine serum FRAP Ferric reducing antioxidant power GAE Gallic acid equivalents KW Kratom aqueous extract KM Kratom methanol extract KA Kratom alkaloid extract MDA Malondialdehyde MG Mitragynine MGO Methylglyoxal MTT 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide ROS Reactive oxygen species AUTHOR CONTRIBUTION All authors made substantial contributions to the conception and design, acquisition of data, or analysis and interpretation of data