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Rat studies examined transected quadriceps muscle (Staresinic 2006), crush injury (Novinscak 2008) and muscle healing impaired by corticosteroids (Pevec 2010)
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thus, the intracellular domain of a fifth-generation CAR is a complex of CD3ζ, CD28, IL-2 and 4-1BB domains [261, 266]
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